Deborah Fielding, chairman of the trustees of St Clare Hospice in Hastingwood, and her husband Ray, both 58 from Great Dunmow, will be joined by St Clare medical director Dr Qamar Abbas from Chelmsford and fundraiser, Bethany Corder, 23 from Abridge, near Epping, plus Linda Pledger, 48, also from Great Dunmow.
Linda, 48, is being sponsored by Alloy Fabweld which makes steel products.
On Saturday, November 9, the five will fly to Siem Reap walking 95km to the Angkor Wat, on the upper plains of Kulen Mountain.